Use PVC Plastisol Coat to Protect Medicine Glass Bottle

Using PVC plastisol coating to protect medicine glass bottles is a feasible technical approach, which can endow glass bottles with functions such as impact resistance, anti-slip, and chemical corrosion resistance. The following is a detailed introduction to this application, including advantages, processes, considerations, and alternative solutions:

Advantages of PVC Plastisol Coating for Pharmaceutical Glass Bottles

• Enhanced Impact Resistance

PVC plastisol forms a flexible protective layer on the glass surface, which can absorb external impacts and reduce the risk of bottle breakage (especially important for transportation and handling).
Example: For glass bottles containing fragile lyophilized powders or injection solutions, the coating can significantly improve packaging reliability.

• Anti-Slip and Improved Handling

• Chemical Corrosion Resistance

PVC exhibits good resistance to most acids, alkalis, and organic solvents, preventing external chemical substances from corroding the glass (e.g., avoiding label glue or cleaning agents from damaging the bottle surface).

• Moisture and Oxygen Barrier

Although the main barrier function still relies on the glass itself, the coating can provide an additional physical barrier to delay the penetration of moisture or gases, which is beneficial for light-sensitive or hygroscopic drugs.

• Labeling and Branding

The coating surface can be printed with clear labels, logos, or usage instructions, improving product 辨识度 (visibility) and reducing label peeling issues.

Typical Coating Processes

The application of PVC plastisol coating generally includes the following steps:

• Surface Preparation

Clean the glass bottle to remove oil, dust, or other contaminants (e.g., using ultrasonic cleaning or high-pressure water rinsing).
Roughen the surface (e.g., via sandblasting) to enhance coating adhesion.

• Coating Application

Dipping Method: Immerse the preheated glass bottle in a pvc plastisol solution, then lift it out to form a uniform liquid film.
Curing: Heat the coated bottle at 200-230°C for 2-5 minutes to solidify the plastisol into a dense, elastic film (thickness usually 800-1500 μm).

• Quality Inspection

Check for coating uniformity, adhesion (via cross-cut test), and impact resistance (via drop test).

Conclusion

PVC plastisol coating is a practical solution for protecting pharmaceutical glass bottles, offering a balance of cost, performance, and processability. However, its application must strictly comply with pharmaceutical regulations, prioritize drug safety, and consider environmental impacts. For high-value or sensitive drugs, alternative materials like silicone or epoxy may be more appropriate. Always validate coating performance through rigorous testing (e.g., stability studies, compatibility tests) before commercialization.